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Metabolomics

Contact:
Dr Ulrich Günther
HWB-NMR, Division of Cancer Studies, CR-UK Institute for Cancer Studies
The University of Birmingham
Vincent Drive
Edgbaston, Birmingham
B15 2TT, United Kingdom

Email: informatics-crn-enquiries[at]cs.bham.ac.uk
Website: http://www.cancerstudies.bham.ac.uk/Research/NMR/Gunther_research.htm


Metabolomics is the study of low molecular weight chemicals found in living organisms. Metabolic profiling has the potential to become an important diagnostic tool. It is already being used in pharmaceutical research and as a tool in clinical diagnostics because it enables an unprejudiced investigation of changes in an organism’s metabolic status during the development of disease, in response to treatment, or following other ways of manipulation. Nuclear Magnetic Resonance (NMR) has been the most frequently used detection method in metabolomics because it allows direct investigation of body fluids such as plasma, serum or urine with only minimal sample treatment.

Metabolomics can reveal important information that is not found through genomics and proteomic approaches. The integration of ‘omics’ data will lead to a wider understanding of the functional organism and will allow great strides to be made in areas such as drug discovery and clinical diagnostics.